정보

• 소속 : 약리학교실
• 직위 : 연구조교수
• 전공 : 임상약리학
• 세부전공 : 계량약리학
• 연락처 : 02 2258 7882
• 이메일 : shan@catholic.ac.kr

논문

• Han, S, Y. H. Kim, H. Y. Choi, D. Soh, J. Kim, J. Nam, J. Kim, K. Bae, and H. Lim (2020). “$\less$p$\greater$First-in-Human Evaluation of the Safety, Tolerability, and Pharmacokinetics of a Neuroprotective Poly (ADP-ribose) Polymerase-1 Inhibitor, JPI-289, in Healthy Volunteers$\less$/p$\greater$”. In: Drug Design, Development and Therapy Volume 14, pp. 3189-3199. DOI: 10.2147/dddt.s235802. URL: https://doi.org/10.2147/dddt.s235802.
• Cho, Y, H. Lim, S. Han, S. K. Yoon, H. Kim, Y. L. Cho, H. Nam, and K. Bae (2019). “Single-dose Intravenous Safety, Tolerability, and Pharmacokinetics and Absolute Bioavailability of~LCB01-0371”. In: Clinical Therapeutics 41.1, pp. 92-106. DOI: 10.1016/j.clinthera.2018.11.009. URL: https://doi.org/10.1016/j.clinthera.2018.11.009.
• Han, S, H. Y. Choi, Y. H. Kim, J. Y. Nam, B. Kim, G. S. Song, H. Lim, and K. Bae (2019). “Randomised clinical trial: safety, tolerability, pharmacokinetics, and pharmacodynamics of single and multiple oral doses of tegoprazan (CJ-12420), a novel potassium-competitive acid blocker, in healthy male subjects”. In: Alimentary Pharmacology & Therapeutics 50.7, pp. 751-759. DOI: 10.1111/apt.15438. URL: https://doi.org/10.1111/apt.15438.
• Han, S, S. Han, K. Kim, H. Lee, and D. Yim (2019). “Usefulness of Bnet, a Simple Linear Metric in Discerning Torsades De Pointes Risks in 28 CiPA Drugs”. In: Frontiers in Pharmacology 10. DOI: 10.3389/fphar.2019.01419. URL: https://doi.org/10.3389/fphar.2019.01419.
• Han, S, Y. Kim, H. Y. Choi, M. Kim, W. J. Kim, H. Park, K. Bae, and H. Lim (2019). “Pharmacokinetic and Pharmacodynamic Modeling and Simulation Analysis of CTB-001, a Recently Developed Generic of Bivalirudin”. In: Pharmaceutical Research 36.10. DOI: 10.1007/s11095-019-2676-6. URL: https://doi.org/10.1007/s11095-019-2676-6.
• Yoon, S, K. Bae, Y. Cho, S. Han, H. Kim, and H. Lim (2019). “Disease Progression Modeling Analysis of the Change of Bone Mineral Density by Postoperative Hormone Therapies in Postmenopausal Patients With Early Breast Cancer”. In: The Journal of Clinical Pharmacology 59.11, pp. 1543-1550. DOI: 10.1002/jcph.1451. URL: https://doi.org/10.1002/jcph.1451.
• Kim, H, S. Han, Y. Cho, S. Yoon, and K. Bae (2018). “Development of R packages: NonCompart' and ncar' for noncompartmental analysis (NCA)”. In: Translational and Clinical Pharmacology 26.1, p. 10. DOI: 10.12793/tcp.2018.26.1.10. URL: https://doi.org/10.12793/tcp.2018.26.1.10.
• Noh, Y, S. Han, S. Choe, J. Jung, J. Jung, A. Hwang, and H. Lim (2018). “Prediction of the human in vivo antiplatelet effect of S- and R-indobufen using population pharmacodynamic modeling and simulation based on in vitro platelet aggregation test”. In: Translational and Clinical Pharmacology 26.4, p. 160. DOI: 10.12793/tcp.2018.26.4.160. URL: https://doi.org/10.12793/tcp.2018.26.4.160.
• Han, S, Y. Cho, S. Yoon, H. Kim, and K. Bae (2017). “Caffsim: simulation of plasma caffeine concentrations implemented as an R package and Web-applications”. In: Translational and Clinical Pharmacology 25.3, p. 141. DOI: 10.12793/tcp.2017.25.3.141. URL: https://doi.org/10.12793/tcp.2017.25.3.141.
• Waters, R. S, J. S. A. Perry, S. Han, B. Bielekova, and T. Gedeon (2017). “The effects of interleukin-2 on immune response regulation”. In: Mathematical Medicine and Biology: A Journal of the IMA 35.1, pp. 79-119. DOI: 10.1093/imammb/dqw021. URL: https://doi.org/10.1093/imammb/dqw021.
• Han, S, Y. C. Lin, T. Wu, A. D. Salgado, I. Mexhitaj, S. C. Wuest, E. Romm, J. Ohayon, R. Goldbach-Mansky, A. Vanderver, A. Marques, C. Toro, P. Williamson, I. Cortese, and B. Bielekova (2014). “Comprehensive Immunophenotyping of Cerebrospinal Fluid Cells in Patients with Neuroimmunological Diseases”. In: The Journal of Immunology 192.6, pp. 2551-2563. DOI: 10.4049/jimmunol.1302884. URL: https://doi.org/10.4049/jimmunol.1302884.
• Perry, J. S. A, S. Han, Q. Xu, M. L. Herman, L. B. Kennedy, G. Csako, and B. Bielekova (2012). “Inhibition of LTi Cell Development by CD25 Blockade Is Associated with Decreased Intrathecal Inflammation in Multiple Sclerosis”. In: Science Translational Medicine 4.145, pp. 145ra106-145ra106. DOI: 10.1126/scitranslmed.3004140. URL: https://doi.org/10.1126/scitranslmed.3004140.
• Han, S, J. Kim, M. Han, H. Sim, K. Kim, S. Yoon, S. Baek, B. Kim, and S. Oh (2011). “SNAI1 is Involved in the Proliferation and Migration of Glioblastoma Cells”. In: Cellular and Molecular Neurobiology 31.3, pp. 489-496. DOI: 10.1007/s10571-010-9643-4. URL: https://doi.org/10.1007/s10571-010-9643-4.
• Wuest, S. C, J. H. Edwan, J. F. Martin, S. Han, J. S. A. Perry, C. M. Cartagena, E. Matsuura, D. Maric, T. A. Waldmann, and B. Bielekova (2011). “A role for interleukin-2 trans-presentation in dendritic cell-mediated T cell activation in humans, as revealed by daclizumab therapy”. In: Nature Medicine 17.5, pp. 604-609. DOI: 10.1038/nm.2365. URL: https://doi.org/10.1038/nm.2365.